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What Are the Signs of Alzheimer's Disease?

What Are the Signs of Alzheimer's Disease?

The symptoms of Alzheimer’s can vary from one person to another. Memory problems are typically one of the first signs of the disease. Decline in non-memory aspects of cognitionsuch as finding the right wordtrouble understanding visual images and spatial relationshipsand impaired reasoning or judgmentmay also signal the early stages of Alzheimer’s. As the disease progressessymptoms become more severe and include increased confusion and behavior changes.

graphic of a woman sitting at a desk with a laptop looking confused.

For most people with Alzheimer’s — those who have the late-onset variety — symptoms first appear in their mid-60s or later. When the disease develops before age 65it’s considered early-onset Alzheimer’swhich can begin as early as a person’s 30salthough this is rare.

Alzheimer’s typically progresses clinically in several stages: preclinicalmild (sometimes called early-stage)moderateand severe (sometimes called late-stage).

Preclinical Alzheimer’s disease

Research suggests that the complex brain changes associated with Alzheimer’ssuch as the formation of amyloid plaques or tau tanglesstart a decade or more before memory and thinking problems appear. This stagein which changes in the brain appear before the onset of dementiais called preclinical Alzheimer’s. Howeverit’s important to note that not everyone with these brain changes develops dementia.

Signs of mild Alzheimer’s disease

In mild Alzheimer’sa person may seem healthy but has more and more trouble making sense of the world around them. The realization that something is wrong often comes gradually to the person and their family. Problems can include:

Alzheimer’s is often diagnosed at this stage.

Signs of moderate Alzheimer’s disease

In this stagemore intensive supervision and care become necessary. These changes and increasing needs can be difficult for many spouses and families. Symptoms may include:

Age-related forgetfulness or signs of dementia infographic. Click to open webpage.
Read and share this infographic to learn about how to tell the difference between age-related forgetfulness and dementia.
  • Increased confusion and memory losssuch as forgetting events or personal history
  • Withdrawal from social activities
  • Inability to learn new things
  • Difficulty with language and problems with readingwritingand working with numbers
  • Difficulty organizing thoughts and thinking logically
  • Shortened attention span
  • Problems coping with new situations
  • Changes in sleeping patternssuch as sleeping more during the day and being restless at night
  • Difficulty carrying out familiarmultistep taskssuch as getting dressed
  • Occasional problems recognizing family and friends
  • Hallucinationsdelusionsand paranoia
  • Impulsive behaviorsuch as undressing at inappropriate times or placesor using vulgar language
  • Inappropriate emotional outbursts  
  • Restlessnessagitationanxietytearfulnesswandering — especially in the late afternoon or evening
  • Repetitive statements or movementoccasional muscle twitches

Signs of severe Alzheimer's disease

People with severe Alzheimer’s cannot communicate and are completely dependent on others for their care. Near the end of lifethe person may be in bed most or all of the time as their body shuts down. Symptoms often include:

  • Inability to communicate
  • No awareness of recent experiences or surroundings
  • Weight loss with little interest in eating
  • Seizures
  • General physical declineincluding dentalskinand foot problems
  • Difficulty swallowing
  • Groaningmoaningor grunting
  • Increased sleeping
  • Loss of bowel and bladder control

A common cause of death for people with Alzheimer’s is aspiration pneumonia. This type of pneumonia develops when a person cannot swallow properly and takes food or liquids into the lungs instead of air.

While there is currently no cure for Alzheimer’sthere are medicines approved by the U.S. Food and Drug Administration that may help treat the disease. There are also changes that can be made to the home environment and daily activities to help a person manage their changes in thinking.

  • Symptoms of mild cognitive impairment

    Some people have a condition called mild cognitive impairment (MCI)which can be an early sign of Alzheimer’s. Howevernot everyone with MCI will develop Alzheimer’s. People with MCI can still take care of themselves and perform their normal activities. MCI memory problems may include:

    • Losing things often
    • Forgetting to go to events or appointments
    • Problems communicating because of difficulty finding words

When to visit the doctor for memory loss

If youa family memberor friend has problems remembering recent events or thinking clearlytalk with a doctor. A doctor may ask questions and conduct various tests and procedures to see what might be causing the symptoms. A doctor may also refer you to a specialistsuch as a neurologistfor further assessment. Learn more in How Is Alzheimer’s Disease Diagnosed? If you or someone you know has recently been diagnosed with Alzheimer’svisit Next Steps After an Alzheimer’s Diagnosis.

You also may be interested in participating in research on cognitive healthagingand dementia. Learn more about volunteering for research to advance Alzheimer’s treatments.

Read about this topic in Spanish. Lea sobre este tema en español.

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For More Information About the Signs of Alzheimer's Disease

NIA Alzheimer’s and related Dementias Education and Referral (ADEAR) Center
800-438-4380
[email protected]
www.nia.nih.gov/alzheimers
The NIA ADEAR Center offers information and publications for download (PDF) about Alzheimer’s and related dementias for familiescaregiversand health professionals. ADEAR Center staff answer telephoneemailand written requests and make referrals to local and national resources.

Alzheimers.gov
www.alzheimers.gov
Explore the Alzheimers.gov website for information and resources on Alzheimer’s and related dementias from across the federal government.

Eldercare Locator
800-677-1116
[email protected]
https://eldercare.acl.gov

MedlinePlus
National Library of Medicine
www.medlineplus.gov

This content is provided by the NIH National Institute on Aging (NIA). NIA scientists and other experts review this content to ensure it is accurate and up to date.