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Liothyronine tablets and capsules

Cytomel

Liothyronine is a replacement thyroid hormone. It is used to treat the more severe conditions in which the thyroid doesn't produce enough thyroxine.

You will need regular blood tests to check your thyroid levelsparticularly at the beginning of this treatment.

If you experience any side-effectsspeak with your doctoras your dose may need adjusting.

Continue reading below

About liothyronine

Type of medicine

A thyroid hormone

Used for

An underactive thyroid gland

Also known as

Cytomel® (USA); Liothyronine sodium

Available as

Tabletscapsules

If you have an underactive thyroid glandit means that your thyroid does not produce enough thyroid hormone. This is a condition known as hypothyroidism. Liothyronine restores the balance of thyroid hormone in your body. It is similar to thyroxinethe hormone which your body produces naturally. Although a medicine called levothyroxine is usually prescribed in preference to liothyronine for people with this conditionliothyronine is given when a fast action is neededas it works more quickly.

Some medicines are not suitable for people with certain conditionsand sometimes a medicine can only be used if extra care is taken. For these reasonsbefore you start taking liothyronine it is important that your doctor knows:

  • If you have heart or blood vessel diseaseor a high blood pressure.

  • If you have either diabetes (diabetes mellitus) or diabetes insipidus.

  • If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescriptionas well as herbal and complementary medicines.

  • If you have ever had an allergic reaction to a medicine.

Continue reading below

  • Before you start the treatmentread the manufacturer's printed information leaflet from inside the pack. It will give you more information about liothyronine and will also provide you with a full list of the side-effects which you could experience from taking it.

  • Take liothyronine exactly as your doctor tells you to. It is usual for your doctor to give you a small dose (such as ½-1 tablet a day) when you first take liothyronineand then for your dose to be gradually increased to two or three tablets dailytaken spaced out throughout the day.

  • Take the tablets with a drink of water. You can take liothyronine either before or after meals.

  • If you forget to take a dosetake it as soon as you remember. Try to take the correct number of doses each day but do not 'double up' to make up for any missed doses.

  • Try to keep your regular appointments with your doctor so that your progress can be monitored. You will need regular blood tests to check your thyroid levelsparticularly in the early stages of your treatment.

  • Continue to take the tablets until your doctor tells you to stop.

  • If you have diabetes you may need to check your blood glucose more frequently as these tablets can affect the levels of sugar in your blood. Your doctor will advise you about this.

  • If you are due to have an operation or any dental treatmentplease tell the person carrying out the treatment that you are taking liothyronine.

Continue reading below

Along with their useful effectsmost medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with liothyronine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Experiencing side-effects may be an indication that your dose needs adjustingso speak with your doctor if you experience any of the symptoms listed below.

Liothyronine side-effects

What can I do if I experience this?

Feeling sick (nausea) or being sick (vomiting)

Eat little and often. Stick to simple foods

Diarrhoea

Drink plenty of water to replace lost fluids

Headache

Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the headaches continuelet your doctor know

The sensation of having a 'thumping' heart (palpitations) or chest pain

Let your doctor know about this as your dose may need adjusting

Feeling restless or shakyflushingsweatingdifficulty sleepinghigh temperature (fever)loss of weightcrampstemporary loss of hair (in children)itchy rash

If any of these become troublesomespeak with your doctor

If you experience any other symptoms which you think may be due to the tabletsspeak with your doctor or pharmacist for further advice.

  • Keep all medicines out of the reach and sight of children.

  • Store in a cooldry placeaway from direct heat and light.

Important information about all medicines

If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicinego to the accident and emergency department of your local hospital. Take the container with youeven if it is empty.

This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.

Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.

If you have any questions about this medicine ask your pharmacist.

Report side effects to a medicine or vaccine

If you experience side effectsyou can report them online through the Yellow Card website.

symptom checker

Unsure about mixing medicines?

Check for possible interactions between medicinessupplements and foods before taking them together.

Further reading and references

Continue reading below

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • Next review due: 19 Jan 2028
  • 19 Jan 2025 | Latest version

    Last updated by

    Michael StewartMRPharmS

    Peer reviewed by

    Sid Dajani
flu eligibility checker

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