<>
.html5-video-player {
border-radius: 32px !important;
}
.html5-video-player:not(.ytp-transparent),
.html5-video-player.unstarted-mode {
border-radius: 32px !important;
}
.w-slider-dot.w-active {
background-color: #ffffff;
border-color: #ffffff;
}
.pagination-dots .w-slider-dot {
border-radius: 100% !important;
border: 1px solid #ffffff;
background: transparent;
margin: 0 !important;
display: block;
}
.w-slider-dot.w-active {
background-color: #ffffff;
border-color: #ffffff;
}
.pagination-dots.w-slider-nav.w-round {
display: flex;
}
.youtube-embed iframe {
display: block;
width: 100%;
height: 100%;
position: absolute;
top: 0;
left: 0;
bottom: 0;
right: 0;
}
/*landscape pagination*/
@media only screen and (max-width: 767px) {
.w-slider-dot.w-active {
background-color: #000000;
border-color: #000000;
}
.w-slider-dot {
border-radius: 100% !important;
border: 1px solid #000000 !important;
background: transparent;
}
.pagination-dots.w-slider-nav.w-round {
display: flex;
justify-content: center;
}
}
#stepSlider {
overflow: visible !important;
}
.step-pagination .swiper-pagination-bullet {
height: 16px;
width: 16px;
border-radius: 50%;
background-color: #fff;
border: 1px solid #fff;
margin: 0px !important;
opacity: 1;
transition: all ease 0.5s;
}
.step-pagination .swiper-pagination-bulletswiper-pagination-bullet-active {
background-color: transparent;
}
/*Hide arrow when no Slides*/
.swiper-button-disabled {
opacity: 0 !important;
pointer-events: none !important;
}
.swiper {
height: 100%;
}
.swiper-wrapper{
display: flex !important;
flex-direction: row !important;
align-items: stretch !important;
}
.swiper-slide {
height: auto !important;
}
.swiper-content {
height: 100% !important;
}
<>
/* Make text look crisper and more legible in all browsers */
body {
-webkit-font-smoothing: antialiased;
-moz-osx-font-smoothing: grayscale;
font-smoothing: antialiased;
text-rendering: optimizeLegibility;
}
/* Focus state for keyboard navigation for the focusable elements */
*[tabindex]:focus-visible,
input[type="file"]:focus-visible {
outline: 0.125rem solid #4d65ff;
outline-offset: 0.125rem;
}
/* Get rid of top margin on first element in any rich text element */
.w-richtext > :not(div):first-child.w-richtext > div:first-child > :first-child {
margin-top: 0 !important;
}
/* Get rid of bottom margin on last element in any rich text element */
.w-richtext>:last-child.w-richtext ol li:last-child.w-richtext ul li:last-child {
margin-bottom: 0 !important;
}
/* Prevent all click and hover interaction with an element */
.pointer-events-off {
pointer-events: none;
}
/* Enables all click and hover interaction with an element */
.pointer-events-on {
pointer-events: auto;
}
/* Create a class of .div-square which maintains a 1:1 dimension of a div */
.div-square::after {
content: "";
display: block;
padding-bottom: 100%;
}
/* Make sure containers never lose their center alignment */
.container-medium,.container-small.container-large {
margin-right: auto !important;
margin-left: auto !important;
}
/*
Make the following elements inherit typography s from the parent and not have hardcoded values.
Important: You will not be able to for example "All Links" in Designer with this CSS applied.
Uncomment this CSS to use it in the project. Leave this message for future hand-off.
*/
/*
a,
.w-input,
.w-select,
.w-tab-link,
.w-nav-link,
.w-dropdown-btn,
.w-dropdown-toggle,
.w-dropdown-link {
color: inherit;
text-decoration: inherit;
font-size: inherit;
}
*/
/* Apply "..." after 3 lines of text */
.text--3lines {
display: -webkit-box;
overflow: hidden;
-webkit-line-clamp: 3;
-webkit-box-orient: vertical;
}
/* Apply "..." after 2 lines of text */
.text--2lines {
display: -webkit-box;
overflow: hidden;
-webkit-line-clamp: 2;
-webkit-box-orient: vertical;
}
/* Adds inline flex display */
.display-inlineflex {
display: inline-flex;
}
/* These classes are never overwritten */
.hide {
display: none !important;
}
@media screen and (max-width: 991px) {
.hide.hide-tablet {
display: none !important;
}
}
@media screen and (max-width: 767px) {
.hide-mobile-landscape{
display: none !important;
}
}
@media screen and (max-width: 479px) {
.hide-mobile{
display: none !important;
}
}
.margin-0 {
margin: 0rem !important;
}
.padding-0 {
padding: 0rem !important;
}
.spacing-clean {
padding: 0rem !important;
margin: 0rem !important;
}
.margin-top {
margin-right: 0rem !important;
margin-bottom: 0rem !important;
margin-left: 0rem !important;
}
.padding-top {
padding-right: 0rem !important;
padding-bottom: 0rem !important;
padding-left: 0rem !important;
}
.margin-right {
margin-top: 0rem !important;
margin-bottom: 0rem !important;
margin-left: 0rem !important;
}
.padding-right {
padding-top: 0rem !important;
padding-bottom: 0rem !important;
padding-left: 0rem !important;
}
.margin-bottom {
margin-top: 0rem !important;
margin-right: 0rem !important;
margin-left: 0rem !important;
}
.padding-bottom {
padding-top: 0rem !important;
padding-right: 0rem !important;
padding-left: 0rem !important;
}
.margin-left {
margin-top: 0rem !important;
margin-right: 0rem !important;
margin-bottom: 0rem !important;
}
.padding-left {
padding-top: 0rem !important;
padding-right: 0rem !important;
padding-bottom: 0rem !important;
}
.margin-horizontal {
margin-top: 0rem !important;
margin-bottom: 0rem !important;
}
.padding-horizontal {
padding-top: 0rem !important;
padding-bottom: 0rem !important;
}
.margin-vertical {
margin-right: 0rem !important;
margin-left: 0rem !important;
}
.padding-vertical {
padding-right: 0rem !important;
padding-left: 0rem !important;
}
.is--disabled-arrow {
opacity: 0.2;
pointer-events: none;
}
@media screen and (max-width: 480px) {
.w-slider-dot.w-active {
background-color: #000000;
opacity: 1;
}
.w-slider-dot {
background-color: #000;
opacity: .5;
}
<>
/* All paragraph elements inside Hubspot form */
.hs-form>p {
margin-top:1rem;
margin-bottom:1rem;
}
/* Set margin right 0 for input wrapper */
.hs-form .input {
margin-right: 0 !important;
}
/* Max width of fieldset element inside form */
.hs-form>fieldset {
max-width: 100% !important;
}
/* Form Input */
.hs-input {
width: 100% !important;
}
/* Radio Inputs */
.hs-input[type=radio] {
width: auto !important;
margin-right: 0.5rem;
min-height: auto !important;
}
/* Checkbox Labels */
.hs-form-checkbox>label {
font-weight: 400 !important;
}
/* Error messages label margin */
.hs-error-msgs>label {
margin-bottom: 0px !important;
}
/* Swiper */
.swiper-fade .swiper-slide:has( ~ .swiper-slide-active) {
opacity: 0 !important;
}
/*Custom Checkbox*/
.hs-input[type=checkbox] {
width: 1rem !important;
height: 1rem !important;
margin-right: 0.5rem !important;
min-height: auto !important;
}
.hs-input[type=checkbox]:focus {
box-shadow: 0 0 3px 1px #bdfd2e;
}
.hs-input[type=checkbox]:checked {
accent-color: #111;
outline: 2px solid #111;
}
.hs-form-booleancheckbox-display>span {
margin-left: 0 !important;
}
.hs-form-field {
width: 100% !important;
}
.multi-image-collection-item:nth-child(2) ~ * {
display: none !important;
}
* {
-webkit-font-smoothing: antialiased;
-moz-osx-font-smoothing: grayscale;
text-rendering: optimizeLegibility;
}
img {
image-rendering: -webkit-optimize-contrast;
}
.navbar.w-nav {
opacity: 1 !important;
}
body > div:not([class*="a"]) {
display: none;
}
.field label {
color: #33475b;
font-size: 15px;
line-height: 1em;
font-weight: 500;
}
legend.hs-field-desc {
color: #537393;
font-size: 11px;
}
.field input {
border-radius: 50px;
font-size: 16px;
line-height: 1.2em;
padding: 10px 20px;
color: #537393;
}
.inputs-list {
list-: none;
padding: 0;
}
.inputs-list input {
margin: 0;
}
.hbspt-form .submitted-message {
padding: 0;
background: transparent;
color: black;
display: grid;
grid-row-gap: 15px;
}
.knowledge-link.w--current {
color: #ff7a00;
}
.pop-up-wrapper {
animation: slide 1s ease 0s 1 normal none;
}
.pop-up-wrapper.close-slide {
animation: slide-close 1s ease 0s 1 normal none;
}
@keyframes slide {
0% {
transform: translateX(108%);
}
100% {
transform: translateX(0%);
}
}
@keyframes slide-close {
0% {
transform: translateX(0%);
}
100% {
transform: translateX(108%);
}
}
/*For the mobile logo slider*/
.track-horizontal-alt {
position: relative!important;
}
.track-horizontal {
position: relative!important;
}
FIDA technology embodies first-principles thinking.
It uses first principles of physics and fluid mechanics to analyze the movement of particles in a fluid.
Thanks to its simplicityit can deliver a wealth of datawith just one assay.
1. Laminar Flow
Laminar flow is a smoothnon-turbulent flow of a fluid pushed through a capillary. In a laminar flow regimethe fluid moves in parallel streams.
2. Taylor Dispersion
Taylor dispersion describes the behaviour of small particles in the flow. As the flow is laminarthe particles will not mix evenlybut instead experience a fluctuating motion. Such a motion results in a dispersion of the particles over time and spaceas they diffuse and move along the flow.
FIDA technology takes advantage of these two principles
by measuring fluorescence of particles in the laminar flow and analysing their dispersion over timewhich allows for calculation of the hydrodynamic radius of a particle of interest.
Additionallyhydrodynamic radius measurement opens door to another crucial biophysical property: the binding between two or more biomolecules
As biomolecules come together and bind in solutiontheir diffusivity (D) decreases; that isthe bound molecules will diffuse slower through the capillary and generate a more extended dispersion profile and diffusion coefficient (D). Using the Stokes-Einstein equationFIDA software reveals the increase in size (Rh) of the molecules as they bind together. Titrating your molecule of interest with its binding partners in a simple FIDA experiment uncovers a wide range of binding parameterssuch as affinity (Kd)derived directly from the hydrodynamic radius and the Stokes-Einstein equation.
The sample of interest is passed through a thin capillary. Due to the difference in velocity between the walls and center of the capillarythe sample shapes into a parabolic profile.
Molecules diffuse radiallyaway from the flow axis. The fluorescence emitted by the molecules is acquired as a Gaussian signal by a high sensitivity detection system and is plotted against time.
The size of the molecules in the sample determines their radial diffusivitywhich in turn defines the extent of sample’s dispersion.
Small molecules diffuse faster and create a more compact dispersion profile. Large molecules diffuse slower, which results in a more extended dispersion profile.
The math behind the software calculations is based on Taylor dispersion phenomena and the Stokes-Einstein equation, which provide a firm base for further calculations.
Watch the video to see how it works
